Description: A potent inhibitor of rat cerebellar Nitric Oxide Synthase (NOS). More potent inhibitor than 7-nitroindazole.
Chemical Formula: C7H4N3O2Br
Molecular Weight: M.W. 242.03
Solubility: Soluble in DMSO.
CAS Number: CAS [74209-34-0]
Active Product: N
Appearance: White to Yellow Crystalline Solid
Handling: Hygroscopic. Protect from Moisture.
Storage: -20 deg C.
Literature Reference: 1. Babbedge, R.C., P.A. Bland-Ward, S.L. Hart, P.K. Moore., Inhibition of Rat Cerebellar Nitric Oxide Synthase by 7-Nitro Indazole and Related Substituted Indazoles., 1993., 110(1):, 225-228., 2. Bland-Ward, P.A., P.K. Moore..
Literature Reference: -Nitro indazole Derivatives are Potent Inhibitors of Brain, Endothelium and Inducible Isoforms of Nitric Oxide Synthase., Life Sciences., 1995., 57(11):, 131-135., 3. Widdowson, P.S., A. Gytre, M.G. Simpson, M. Farnworth, D. Dunn, R.B. Moore, I. Wyatt, E.A. Lock..
Literature Reference: Possible Role of Nitric Oxide in the Development of L-2-Chloropropionic Acid-Induced Cerebellar Granule Cell Necrosis., British Journal of Pharmacology., 1996., 117(8):, 1761-1767..